Plenary lecture – Wednesday, July 1, 2026

Picking the right nose – a successful industry-academia collaboration

Abstract

The development of locally and systemically acting nasal drugs requires a deep understanding of human anatomy and aerosol deposition dynamics. Digital Human Modeling (DHM) is fundamentally transforming this process by bridging the gap between digital anatomical data and physical, real-world testing.

This presentation will explore how DHM, combined with advanced 3D printing technologies, enables the creation of highly accurate, anatomically representative in vitro models. By transitioning from digital geometries to functional physical platforms, pharmaceutical researchers can conduct detailed, region-specific analyses of complex drug delivery systems in a controlled laboratory environment.

We will discuss the collaborative journey of developing these testing platforms, highlighting how the integration of mechanical engineering methodologies and pharmaceutical sciences leads to more robust, replicable, and cost-effective tools for the development of next-generation therapies.

Jernej Grmaš, PhD

Head of Physical Analytics, Lek a Sandoz company

Dr. Jernej Grmaš is Head of Physical Analytics at Lek, a Sandoz company, where he leads method development and strategic oversight for over 25 analytical techniques spanning material characterization, microscopy, rheology, and inhalation/nasal spray testing. His work focuses on supporting the development of complex generic products, including locally acting formulations and products requiring in vitro bioequivalence and characterization studies.

With more than 17 years of experience in pharmaceutical R&D in various roles, Dr. Grmaš has contributed to numerous product development programs and scientific publications. He is also experienced in digital transformation, having led the global rollout of a Digital Lab Platform within Sandoz. He holds a PhD in Biomedicine and a Master of Pharmacy from the University of Ljubljana.